Publications

  • Qinghe Zeng, Landon Flemming, Yuanzhou Chen, Thomas Mazumder, Heinz Hammerlindl, Greg M. Allen, Ricardo Almeida, Jasper Z. Williams, Rogelio A. Hernández-López, Ania-Ariadna Baetica, Sara E. Meyer, Joseph A. Fraietta, Justin Eyquem, Chun J. Ye, Wendell A. Lim, Qizhi Tang, Tejal A. Desai*, Xiao Huang*. Programmable CAR-engaging particles rewire human CAR T-cell signaling for sustainable ex vivo expansion. Nature Communications, in press.bioRiv, 2025.

  • Pierce Hadley, Yuanzhou Chen, Lariana Cline, Zhiyuan Han, Qizhi Tang, Xiao Huang*, Tejal Desai*. Precise surface functionalization of PLGA particles for human T cell modulation. Nature Protocols, 2023, 18: 3289-3321. https://www.nature.com/articles/s41596-023-00887-8

  • Joel A. Finbloom, Cindy Huynh, Xiao Huang, Tejal Desai*. Bioinspired nanotopographical design of drug delivery systems. Nature Review Bioengineering, 2023, 1: 139-152.

  • Xiao Huang, Jasper Z. Williams, Ryan Chang, Zhongbo Li, Cassandra E. Burnett, Rogelio Hernandez-Lopez, Initha Setiady, Eric Gai, David M. Patterson, Wei Yu, Kole T. Roybal, Wendell A. Lim, Tejal A. Desai. DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation. Nature Nanotechnology, 2021, 16: 214-223. https://www.nature.com/articles/s41565-020-00813-z

  • Xiao Huang, Xiaoyu Shi, Mollie Eva Hansen, Initha Setiady, Cameron L. Nemeth, Anna Celli, Bo Huang, Theodora Mauro, Michael Koval, Tejal A. Desai. Nanotopography enhances dynamic remodeling of tight junction proteins through cytosolic liquid complexes. ACS nano, 2020, 14: 13192-13202. https://pubs.acs.org/doi/10.1021/acsnano.0c04866

  • Xiao Huang, Qirui Hu, Yifan Lai, Demosthenes P. Morales, Dennis O. Clegg, Norbert O. Reich. Light-patterned RNA interference of 3D-cultured human embryonic stem cells. Advanced Materials, 2016, 28 (48): 10732-10737.

  • Xiao Huang, Qirui Hu, Gary B. Braun, Alessia Pallaoro, Demosthenes P. Morales, Joseph A. Zasadzinski, Dennis O. Clegg, Norbert O. Reich. Light-activated RNA interference in human embryonic stem cells. Biomaterials, 2015, 63: 70-79.

  • Xiao Huang, Alessia Pallaoro, Gary B. Braun, Demosthenes P. Morales, Maria O. Ogunyankin, Joseph Zasadzinski, and Norbert O. Reich. Modular plasmonic nanocarriers for efficient and targeted delivery of cancer-therapeutic siRNA.
    Nano Letters, 2014, 14 (4): 2046-2051.